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Abstract #3517

Time-efficient high resolution diffusion weighted SSFP measurements at 14.1T

Dario Bosch1,2, Gisela Hagberg1,2, Rolf Pohmann1, Thomas Shiozawa-Bayer3, Bernhard Hirt3, and Klaus Scheffler1,2

1High-Field Magnetic Resonance Center, Max Planck Institute for Biological Cybernetics, Tübingen, Germany, 2Biomedical Magnetic Resonance, University Hospital Tübingen, Tübingen, Germany, 3Institute for clinical anatomy and cellanalysis, Department of Anatomy, University Hospital Tübingen, Tübingen, Germany

This study investigates the use of diffusion weighted SSFP imaging for high-resolution diffusivity measurements of post-mortem tissue, using two different models (Wu-Buxton and Freed) and draws a comparison to conventional DW SE-Measurements. A toolbox was developed to optimize SSFP imaging parameters for selected tissue regions which was then used successfully. We showed that the SSFP approach is highly valuable for time-efficient high-resolution post-mortem diffusion weighted imaging.

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