Abstract #3517

Time-efficient high resolution diffusion weighted SSFP measurements at 14.1T

Dario Bosch^1,2, Gisela Hagberg^1,2, Rolf Pohmann¹, Thomas Shiozawa-Bayer³, Bernhard Hirt³, and Klaus Scheffler^1,2

¹High-Field Magnetic Resonance Center, Max Planck Institute for Biological Cybernetics, Tübingen, Germany, ²Biomedical Magnetic Resonance, University Hospital Tübingen, Tübingen, Germany, ³Institute for clinical anatomy and cellanalysis, Department of Anatomy, University Hospital Tübingen, Tübingen, Germany

This study investigates the use of diffusion weighted SSFP imaging for high-resolution diffusivity measurements of post-mortem tissue, using two different models (Wu-Buxton and Freed) and draws a comparison to conventional DW SE-Measurements. A toolbox was developed to optimize SSFP imaging parameters for selected tissue regions which was then used successfully. We showed that the SSFP approach is highly valuable for time-efficient high-resolution post-mortem diffusion weighted imaging.

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