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Abstract #3569

Improving Tractography in Baby Diffusion MRI via Asymmetric Spectrum Imaging

Ye Wu1, Weili Lin1, Dinggang Shen1, Pew-Thian Yap1, and the UNC/UMN Baby Connectome Project Consortium Consortium1

1Department of Radiology and BRIC, University of North Carolina, Chapel Hill, Chapel Hill, NC, United States

Fiber tractography in baby diffusion MRI is challenging due to the low and spatially-varying diffusion anisotropy. In this abstract, we will introduce a method called asymmetric spectrum imaging (ASI) to improve estimation of white matter pathways in the baby brain by (1) incorporating an asymmetric fiber orientation model to help resolve subvoxel fiber configurations such as fanning and bending, and (2) explicitly modeling the spectrum of diffusion typical in the developing brain.

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