Axonal degeneration is a hallmark of many neuropathologies, with a defined time course presenting distinct histological features. In single fiber regions, the tensor model provides reliable information in early and chronic phases of axonal damage. However, said model cannot accurately determine per-bundle characteristics in voxels occupied by axonal populations with different orientations. We evaluated two multiple-fiber methods in an animal model of axonal degeneration (unilateral retinal ischemia) to provide information about the sensitivity of these models related to microstructural changes occuring in the acute and early chronic stages of pathology in a crossing fiber region.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords