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Abstract #3630

Delineation of thalamic substructures in ultra-high b-value DWI-measurement with reasonable acquisition time

Nils Christoph Nuessle1, Benjamin Bender1, and Uwe Klose1

1Diagnostic and interventional Neuroradiology, University Hospital Tuebingen, Tuebingen, Germany

The purpose of this study was to evaluate the capability of optimized and faster ultra-high b-value DWI in separating and identifying intrathalamic substructures compared to a previously described protocol. 7 subjects underwent MR-imaging, including T1 MPRAGE and two DWI sequences at 0 and 5000 s/mm2. DWI was performed with 64 directions and 5 averages (17:56 min) and with 6 directions and 25 averages (8:23 min). Intrathalamic substructures were semi-automatically delineate 4mm above AC/PC line. Accordance between the original sequence and the new speeded-up measurement was high. Acquisition time was reduced by more than 50 % with comparable results.

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