Details a novel bi-component polymer Taxon (textile water filled tubes) anisotropic diffusion phantom providing 0.8 microndiameter tubes, packing density of 106 per mm2, water fraction of over 45% matched to human axon histology with parametric control of water compartment (intra/extra axon), size, density, angle dispersion that can be manufactured to supply hundreds of laboratories. Observed human tissue range FA (0.6-01.0), MD and RD in observed range. Providing ground truth measurement to advance and calibrate anisotropic diffusion measurement. Micro-CT and diffusion MRI indicate high water content in agreement with MRI and non MRI measurements.
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