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Abstract #3680

HCC screening with abbreviated MRI: retrospective comparison of noncontrast, dynamic-contrast enhanced and hepatobiliary phase protocols post gadoxetic acid

Naik Vietti Violi1, Miriam Hulkower2, Joseph Liao2, Gabriela Hernandez-Meza3, Katherine Smith4, Xing Ching2, Joseph Song2, Eitan Novogrodsky5, Daniela Said1, Shingo Kihira2, Mark Berger2, Maxwell Segall1, Keith Sigel6, Mary Sun3, Dillan Villavisanis3, Claude B Sirlin7, Sara Lewis1,2, and Bachir Taouli1,2

1Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States, 2Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States, 3Icahn School of Medicine at Mount Sinai, New York, NY, United States, 4Columbia University, New York, NY, United States, 5Radiology, Albert Einstein College of Medicine, New York, NY, United States, 6Infectious diseases, Icahn School of Medicine at Mount Sinai, New York, NY, United States, 7Radiology, UC San Diego Medical Center, San Diego, CA, United States

In this study, we compare the performance of different abbreviated MRI (AMRI) protocols using 3 different sets: noncontrast, dynamic T1WI, and hepatobiliary phase (HBP) post gadoxetic acid for hepatocellular carcinoma (HCC) screening in 238 patients at risk. Our results showed that performance of noncontrast AMRI was low, while AMRI using dynamic T1WI and AMRI including HBP showed equivalent sensitivity for HCC detection with slightly better specificity for dynamic T1W. These results need verification in a larger study.

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