Abstract #3697

Comparisons of resting-state networks obtained at 3 and 7 Tesla MRI in anesthetized rhesus monkey

Chan-Ung Park¹, Eunha Baeg¹, Boo-Hee Choi¹, Bo-yong Park ^1,2, Hyunjin Park ^1,3, and Seong-Gi Kim^1,4

¹Center for Neuroscience Imaging Research, Institute for Basic Science, Suwon, Korea, Republic of, ²Department of Electrical and Computer Engineering, Sungkyunkwan University, Suwon, Korea, Republic of, ³School of Electronic and Electrical Engineering, Sungkyunkwan University, Suwon, Korea, Republic of, ⁴Department of Biomedical Engineering, Sungkyunkwan University, Suwon, Korea, Republic of

Understanding resting-state fMRI (rsfMRI) is an important issue to identify the functional principles of the normal and pathological brain networks. Despite the importance in comprehending network as a whole, a deeper understanding of the resting-state networks is limited due to the lack of a proper animal model. Here, we used anesthetized non-human primate (NHP) for understanding rsfMRI networks commonly detected in humans. BOLD and MION-enhanced CBV rsfMRI networks were obtained at 3T and 7T. Stable eight cortical networks were observed from MION experiments at 3T and 7T, and similar networks were also detected from 7T BOLD due to enhanced sensitivity.

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