We provide a fine-grained description of the network structure and topology of the mouse connectome with voxel-resolution. We show that structural connectivity hubs can be spatially segregated into a dichotomic set of neural sink and neural source regions, and that functional and structural hubs show concordant neuro-anatomical topography. We finally demonstrate that the modular structure of the mouse connectome recapitulates large-scale fMRI networks of the mouse brain, including a default mode network core community, which is characterized by high structural resilience. Our results lay the foundation for topologically-driven targeted manipulations of the mouse connectome.
This abstract and the presentation materials are available to members only; a login is required.