Abstract #3707

The correlation between cerebral venous oxygen saturation change and cognitive score in Alzheimer's disease patients by using susceptibility weighted imaging mapping

Junyi Dong¹, Yanwei Miao¹, Xiaoxin Li¹, Liang Han¹, Lizhi Xie², Qingwei Song¹, and Ailian Liu¹

¹Department of Radiology, First Affiliated Hospital of Dalian Medical University, Dalian,116011,China, Dalian, China, ²GE Healthcare, Beijing, China

Alzheimer's disease (AD) is a progressive neurodegenerative disease and vascular factors may be important in the development and progression of AD[1]. Magnetic susceptibility weighted imaging (SWI) is widely used in the diagnosis of central nervous system diseases, and venous oxygen content is the basis of SWI angiography. The venous blood oxygen level can be reflected by measuring the phase value of venous blood. This study first made use of SWI mapping (SWIM) to measure the change of magnetic susceptibility and the change of blood oxygen and then explores the correlation between cerebral venous oxygen saturation change and cognitive score in AD patients

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