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Abstract #3734

IVIM-based cerebral perfusion (in ml/100g/min) values at rest, hypercapnia and ischemia in an MCA occlusion model

Mira Liu1, Yong Jeong2, Niloufar Saadat1, Gregory Christoforidis1, and Timothy Carroll1

1Department of Radiology, University of Chicago, Chicago, IL, United States, 2Bioengineering and Biomedical Engineering, Northwestern, Chicago, IL, United States

This is a preliminary study of intravoxel incoherent motion (IVIM) in a two day study of normocapnia, hypercapnia, and post middle cerebral artery occlusion. It was established that IVIM perfusion values are linearly correlated to the reference perfusion values under a variety of physiologic states meaning IVIM perfusion values can be easily quantified. Once scaled, the IVIM CBF of white matter and grey matter normocapnia and post-occlusion cortex on both hemispheres were strongly correlated to the reference standard.

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