Abstract #3766

R1 and R2 characterization of human blood with phase-cycled balanced steady-state free precession (bSSFP)

Marlon Pérez-Rodas^1,2, Hildegard Schulz¹, Rolf Pohmann¹, Klaus Scheffler^1,3, and Rahel Heule¹

¹High-Field MR Center, Max Planck Institute for Biological Cybernetics, Tübingen, Germany, ²Graduate Training Centre of Neuroscience, IMPRS for Cognitive and Systems Neuroscience, University of Tübingen, Tübingen, Germany, ³Department of Biomedical Magnetic Resonance, University of Tübingen, Tübingen, Germany

Balanced steady-state free precession (bSSFP) sequences have received increased interest for functional BOLD experiments since, in contrast to conventional EPI-based techniques, they are not prone to geometric distortions in the phase encoding direction. Characterization of measured BOLD signal changes requires consideration of extravascular as well as intravascular contributions. Knowledge about the relaxation rates of human blood is a prerequisite to quantify the intravascular contribution to the BOLD effect. Here, R₁ and R₂ relaxation rates of blood samples are intrinsically obtained from a series of phase-cycled bSSFP scans to account for the repetition time dependence of R₂ due to rapid refocusing.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.