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Abstract #3765

Longitudinal study of BOLD HRF in human cortex

Amanda J Taylor1, Xiaowei Zou2, Jung Hwan Kim2, and David Ress2

1Neuroscience, Baylor College of Medicine, Houston, TX, United States, 2Baylor College of Medicine, Houston, TX, United States

A simple audiovisual stimulus combined with a fast-paced task evoked a strong HRF across a majority of cerebral cortex during four scanning sessions to measure the repeatability of BOLD over time. HRFs were characterized by spatial and temporal parameters and showed remarkable correlation across the time points, which spanned three hours, three days, and three months. Results showed that HRFs are repeatable for consistent quantification of neurovascular coupling.

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