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Abstract #3776

The latency differentiates BOLD responses elicited by congruent and incongruent McGurk audio-visual stimulus pairs

Ren-Horng Wang1, Shu-Yu Huang1, Hsin-Ju Lee2,3, Wen-Jui Kuo3, and Fa-Hsuan Lin2,4,5

1Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan, 2National Taiwan University, Taipei, Taiwan, 3National Yang-Ming University, Taipei, Taiwan, 4Department of Mediacl Biophysics, University of Toronto, Toronto, ON, Canada, 5Department of Neuroscience and Biomedical Engineering, Aalto University, Espoo, Finland

We used fast fMRI sampled at the 10-Hz rate to study fMRI timing in audiovisual integration. Using the McGurk protocol, we found that the superior temporal gyrus (STG) had significant BOLD time-to-half (TTH) difference between the McGurk and congruent audiovisual stimuli pairs. The significance of TTH difference between congruent and McGurk was progressively more significant from posterior to anterior regions (p-values at visual cortex, lateral occipital lob, occipital parietal junction, STG, and auditory cortex were 0.13, 0.12, 0.05, 0.02, and 0.01, respectively), suggesting that incongruent audio-visual stimuli cause more delayed the brain response at regions closer to primary auditory processing.

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