Abstract #3776

The latency differentiates BOLD responses elicited by congruent and incongruent McGurk audio-visual stimulus pairs

Ren-Horng Wang¹, Shu-Yu Huang¹, Hsin-Ju Lee^2,3, Wen-Jui Kuo³, and Fa-Hsuan Lin^2,4,5

¹Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan, ²National Taiwan University, Taipei, Taiwan, ³National Yang-Ming University, Taipei, Taiwan, ⁴Department of Mediacl Biophysics, University of Toronto, Toronto, ON, Canada, ⁵Department of Neuroscience and Biomedical Engineering, Aalto University, Espoo, Finland

We used fast fMRI sampled at the 10-Hz rate to study fMRI timing in audiovisual integration. Using the McGurk protocol, we found that the superior temporal gyrus (STG) had significant BOLD time-to-half (TTH) difference between the McGurk and congruent audiovisual stimuli pairs. The significance of TTH difference between congruent and McGurk was progressively more significant from posterior to anterior regions (p-values at visual cortex, lateral occipital lob, occipital parietal junction, STG, and auditory cortex were 0.13, 0.12, 0.05, 0.02, and 0.01, respectively), suggesting that incongruent audio-visual stimuli cause more delayed the brain response at regions closer to primary auditory processing.

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