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Abstract #3777

Electrical conductivity as a potential mean to decouple the hemodynamic response from fMRI

Rita Schmidt1

1Neurobiology, Weizmann Institute of Science, Rehovot, Israel

MR electrical properties imaging offers new means for probing physiological information in-vivo. The interest for fMRI lies in the dependence of electrical conductivity on structural macroscopic changes and on ionic concentration changes. In-vivo electrical conductivity acquisition has the potential to provide the means to decouple the hemodynamic response from fMRI. Changes in electrical conductivity can be measured using phase changes in a spin-echo experiment. We compared BOLD fMRI with phase changes in SE-EPI using basic visual task paradigm at 3T MRI, which showed faster time response and more localized spatial activation. Further study is required to analyze possible contributing factors.

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