Abstract #3797

Dynamic up- and down-regulation of large-scale cortical networks during task-on and task-off periods.

Katarzyna Anna Kazimierczak^1,2, Karsten Specht^1,3,4, Justyna Beresniewicz^1,2, Kristiina Kompus^1,2, René Westerhausen⁵, Renate Grüner^4,6,7, Lars Ersland^1,2,8, and Kenneth Hugdahl^1,2,6,9

¹Department of Biological and Medical Psychology, University of Bergen, Bergen, Norway, ²NORMENT Centre of Excellence, University of Oslo, Oslo, Norway, ³Department of Education, The Arctic University of Norway, Tromsø, Norway, ⁴Mohn Medical Imaging and Visualization Centre, Haukeland University Hospital, Bergen, Norway, ⁵Institute of Psychology, Univeristy of Oslo, Oslo, Norway, ⁶Department of Radiology, Haukeland University Hospital, Bergen, Norway, ⁷Department of Physics and Technology, University of Bergen, Bergen, Norway, ⁸Department of Clinical Engineering, Haukeland University Hospital, Bergen, Norway, ⁹Division of Psychiatry, Haukeland University Hospital, Bergen, Norway

This study was intended to capture the dynamics of networks up- and down-regulation over time, with focus on the extrinsic mode network (EMN) and the default mode network (DMN), using functional magnetic resonance imaging (fMRI). Finite impulse response function (FIR) featured in the SPM software package was used to estimate the BOLD response. The results featured initial rapid activation of EMN in task-periods, while DMN began to drift towards up-regulation already by the end of the task-period.

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