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Abstract #3797

Dynamic up- and down-regulation of large-scale cortical networks during task-on and task-off periods.

Katarzyna Anna Kazimierczak1,2, Karsten Specht1,3,4, Justyna Beresniewicz1,2, Kristiina Kompus1,2, René Westerhausen5, Renate Grüner4,6,7, Lars Ersland1,2,8, and Kenneth Hugdahl1,2,6,9

1Department of Biological and Medical Psychology, University of Bergen, Bergen, Norway, 2NORMENT Centre of Excellence, University of Oslo, Oslo, Norway, 3Department of Education, The Arctic University of Norway, Tromsø, Norway, 4Mohn Medical Imaging and Visualization Centre, Haukeland University Hospital, Bergen, Norway, 5Institute of Psychology, Univeristy of Oslo, Oslo, Norway, 6Department of Radiology, Haukeland University Hospital, Bergen, Norway, 7Department of Physics and Technology, University of Bergen, Bergen, Norway, 8Department of Clinical Engineering, Haukeland University Hospital, Bergen, Norway, 9Division of Psychiatry, Haukeland University Hospital, Bergen, Norway

This study was intended to capture the dynamics of networks up- and down-regulation over time, with focus on the extrinsic mode network (EMN) and the default mode network (DMN), using functional magnetic resonance imaging (fMRI). Finite impulse response function (FIR) featured in the SPM software package was used to estimate the BOLD response. The results featured initial rapid activation of EMN in task-periods, while DMN began to drift towards up-regulation already by the end of the task-period.

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