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Abstract #3826

Design, evaluation and application of a 16-channel Frequency Synthesizer Module for Thermal Magnetic Resonance

Haopeng Han1, Shuailin Wang2, Thomas Wilhelm Eigentler1, Lukas Winter3, Eckhard Grass4,5, and Thoralf Niendorf1,6,7

1Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany, 2Beijing Deepvision Technology Co., Ltd., Beijing, China, 3Physikalische Technische Bundesanstalt (PTB), Berlin, Germany, 4IHP – Leibniz-Institut für innovative Mikroelektronik, Frankfurt (Oder), Germany, 5Institute of Computer Science, Humboldt-Universität zu Berlin, Berlin, Germany, 6Experimental and Clinical Research Center (ECRC), a joint cooperation between the Charité Medical Faculty and the Max Delbrück Center for Molecular Medicine, Berlin, Germany, 7MRI.TOOLS GmbH, Berlin, Germany

Thermal Magnetic Resonance makes use of the physics of the radio frequency fields applied at ultrahigh field magnetic resonance imaging. While UHF-MRI enables measuring temperature in vivo, highly localized power deposition can be achieved by interfering RF waveforms with a shortened wavelength. This constitutes a means for supervised in vivo temperature modulation. The number of RF signals and the signals’ properties greatly affect the heating performance. In this work, a 16-channel frequency synthesizer module was developed as an RF signal source for Thermal MR. Preliminary experiments were conducted to demonstrate that the proposed module is suitable for Thermal MR.

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