Thermal Magnetic Resonance makes use of the physics of the radio frequency fields applied at ultrahigh field magnetic resonance imaging. While UHF-MRI enables measuring temperature in vivo, highly localized power deposition can be achieved by interfering RF waveforms with a shortened wavelength. This constitutes a means for supervised in vivo temperature modulation. The number of RF signals and the signals’ properties greatly affect the heating performance. In this work, a 16-channel frequency synthesizer module was developed as an RF signal source for Thermal MR. Preliminary experiments were conducted to demonstrate that the proposed module is suitable for Thermal MR.