Abstract #3882

Weaker Intra- and Inter-nodal Connectivity of Resting State Networks in Drug-naive Attention-Deficit/Hyperactivity Disorder

Yingxue Gao¹, Hailong Li¹, Xuan Bu¹, Xinyu Hu¹, Xiaoxiao Hu¹, Lianqing Zhang¹, Lu Lu¹, Shi Tang¹, Kaili Liang¹, Yanlin Wang¹, Chuang Yang², and Xiaoqi Huang¹

¹Department of Radiology, Huaxi Magnetic Resonance Research Centre (HMRRC), Chengdu, China, ²Department of Psychiatry, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China

We used group-level independent component analysis (ICA) to investigate functional network connectivity in drug-naïve ADHD children. We extracted eight resting state networks and found that lower intranodal and internodal functional connectivity among executive control, precuneus and default mode networks in ADHD children compared to controls, especially located in prefrontal and parietal regions. This finding may provide new insights into functional connectivity alterations in ADHD children and promote the exploration of functional network connectivity in future researches.

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