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Abstract #3881

Changes in resting state networks in major depression following ketamine administration

Jennifer Evans1 and Carlos Zarate1

1ETPB, NIH, Bethesda, MD, United States

Recently, it has been shown that individual classification of subjects across scans is possible using correlation matrices derived from their resting state data. In the current study, a cohort of patient with major depression and healthy controls each had five resting state fMRI scans over the course of a double blind randomized placebo controlled cross-over ketamine infusion study We apply this classification scheme to our data to see if we can link individual functional connectivity profiles to behavioral improvements after ketamine.

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