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Abstract #3930

Quiet, Low-Distortion Whole Brain T2-BOLD fMRI at 7T

Brian Burns1, Trevor Flynn2, Ana Beatriz Solana3, Peng Cao2, Angela Jakary2, Anne Menini1, Florian Wiesinger3, and Peder Larson2

1MR Applied Sciences Lab West, GE Heathcare, San Francisco, CA, United States, 2Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States, 3MR Applied Sciences Lab Europe, GE Heathcare, Munich, Germany

EPI-based 7T fMRI techniques suffer from spatial distortions in areas of B0 inhomogeneity, signal dropout near air-tissue boundaries, and gradient induced acoustic noise can be as high as 115-120dB. We have developed fast, quiet, low-distortion whole brain 7T fMRI by using the T2-prepared Rotating Ultrafast Imaging Sequence (RUFIS). RUFIS is a ZTE technique with low gradient switching, so it does not suffer from many of the problems of EPI-based methods. It has no spatial distortions and signal dropout, and is 40dB quieter than standard EPI-based technique. Whole-brain 3mm isotropic results for resting state and task-based 7T fMRI experiments are shown.

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