Single-shot accelerated volumetric Arterial Spin Labeling is desirable for studies of flow and function modulation but it typically degrades image quality relative to multi-shot interleaved acquisitions. We report a Stack of Spirals RARE acquisition with rotation of spirals between slice encodes and repetitions. This acquisition supports high quality single-shot reconstruction with 3D parallel imaging/compressed sensing while retaining the ability to perform conventional interleaved reconstruction of time averaged perfusion. Application of the sequence to quantification of resting state network fluctuations is demonstrated.
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