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Abstract #3931

Rotated Stack of Spirals 3D RARE for Single-shot Volumetric ASL Acquisition

Fanny Munsch1, Manuel Taso1, Li Zhao2, R. Marc Lebel3, Arnaud Guidon4, and David C Alsop1

1Division of MRI research, Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States, 2Diagnostic Imaging and Radiology, Children’s National Medical Center, Washington, DC, United States, 3Global MR Applications and Workflow, GE Healthcare, Calgary, AB, Canada, 4Global MR Applications and Workflow, GE Healthcare, Boston, MA, United States

Single-shot accelerated volumetric Arterial Spin Labeling is desirable for studies of flow and function modulation but it typically degrades image quality relative to multi-shot interleaved acquisitions. We report a Stack of Spirals RARE acquisition with rotation of spirals between slice encodes and repetitions. This acquisition supports high quality single-shot reconstruction with 3D parallel imaging/compressed sensing while retaining the ability to perform conventional interleaved reconstruction of time averaged perfusion. Application of the sequence to quantification of resting state network fluctuations is demonstrated.

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