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Abstract #3964

In Vivo Cardiac MR Elastography with a Gravitational Transducer

Ayse Sila Dokumaci1, Torben Schneider2, Daniel Fovargue1, Emma Burnhope1, Myrianthi Hadjicharalambous1, Stefan-Heinz Hoelzl1, Jelizaveta Sudakova1, Adela Capilnasiu1, Marian Troelstra1,3, Sweta Sethi1,4, Tevfik Ismail1, Ralph Sinkus1, and David Alexander Nordsletten1,5

1Division of Imaging Sciences and Biomedical Engineering, King’s College London, London, United Kingdom, 2Philips Healthcare, Guildford, Surrey, United Kingdom, 3Amsterdam UMC, Amsterdam, Netherlands, 4Guy's and St.Thomas' NHS Foundation Trust, London, United Kingdom, 5Department of Biomedical Engineering and Cardiac Surgery, University of Michigan, Ann Arbor, MI, United States

MR Elastography is beneficial in measuring the stiffness values of tissues which can change in disease. Nevertheless, cardiac MR Elastography is not only challenging from the acquisition side but also from the reconstruction side because of the higher stiffness values expected in the cardiac muscle compared to the other organs in which MR Elastography is commonly applied. Here, we present data in healthy subjects and a patient acquired with the gravitational transducer with a novel synchronising strategy in combination with a single-shot SE-EPI-MRE sequence employing second-order motion compensated motion encoding gradients with and without ZOnal Oblique Multislice Imaging.

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