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Abstract #3972

Repeatability and Clinical Performance of Non-gated, Free-breathing, MR Elastography (MRE) of the Liver

Jiahui Li1, Bogdan Dzyubak1, Kevin J. Glaser1, Ziying Yin1, Jun Chen1, Alina Allen2, Sudhakar K. Venkatesh1, Armando Manduca1, Vijay Shah2, Richard L. Ehman1, and Meng Yin1

1Radiology, Mayo Clinic, Rochester, MN, United States, 2Gastroenterology, Mayo Clinic, Rochester, MN, United States

While conventional MRE is easily performed during suspended respiration, a free breathing MRE technique would be advantageous in pediatric and other patients. We assessed the repeatability of free-breathing MRE in comparison to conventional breath held acquisitions in volunteers and the clinical performance of free-breathing MRE in a cohort of 56 patients with chronic liver diseases. Results demonstrated comparable repeatability and excellent agreement of the averaged liver stiffnesses measured using the two techniques. In summary, free-breathing MRE provides highly repeatable and accurate liver stiffness values.

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