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Abstract #3979

Effects of Multiple Contrast Agents in Multi-Modality Imaging for Liver Embolizations: A Preliminary MR Analysis

Carson A Hoffman1, Paul A Laeseke2, Oliver A Wieben1,2, and Diego A Hernando1,2

1Medical Physics, University of Wisconsin Madison, Madison, WI, United States, 2Radiology, University of Wisconsin Madison, Madison, WI, United States

Transarterial embolization (TAE) is a standard treatment for liver tumors and results in stasis and an accumulation of iodinated contrast agent in the liver. This study demonstrated that when iodinated contrast agents are present in MR, a T1 and T2 shortening effect can occur. We completed a preliminary analysis investigating pre- and post-TAE MR signal changes in the presence of iodine and gadolinium based contrast agents in-vivo (pilot swine study) and in phantoms. Understanding variations in MR images caused by contrast agents used for other modalities could help reduce errors in multimodality imaging studies.

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