The study of neurometabolites and the detection of glucose in the brain has relied on anesthetized animals. Prolonged periods of anesthesia required for these studies may affect these metabolites and the ability to interpret glucose detection in the brain. However, performing post-mortem studies of neurometabolites and glucose detection in the brain is difficult to interpret because of rapid degradation. In this study, we utilized focal beam microwave irradiation (FBMI) without anesthesia to collect brain tissue and determine whether there is postmortem degradation of neurometabolites and glucose using 1H-NMR and glucoCEST.
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