Abstract #3991

Thermal sensitive pH imaging using CEST

Yuki Kanazawa¹, Daiki Chiba¹, Masafumi Harada¹, Tosiaki Miyati², Mitsuharu Miyoshi³, Hiroaki Hayashi², Yuki Matsumoto¹, Takashi Abe¹, and Akihiro Haga¹

¹Tokushima University, Tokushima, Japan, ²Kanazawa University, Kanazawa, Japan, ³Global MR Applications and Workflow, GE Healthcare Japan, Tokyo, Japan

We performed phantom study with CEST and clarified pH change depending on temperature. Linear regression analysis shows a strong significant correlation between temperature and MTR_asym at 2.0 ppm in all egg white albumin samples (R² > 0.78, P < 0.05). As pH changed with temperature, we found that the offset frequency of MTR_asym was more sensitive at 2.0 ppm than that at 3.5 ppm.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.