Abstract #4059

Joint placental angiography with perfusion and apparent oxygenation mapping

Laurence H Jackson¹, Jana Hutter¹, Anthony N Price¹, Alison Ho², Laura McCabe^1,3, Thomas A Roberts¹, Maria Deprez¹, Lucy Chappell², Mary Rutherford^1,3, Enrico De Vita¹, and Joseph V Hajnal^1,3

¹Biomedical Engineering,School of Biomedical Engineering & Imaging Sciences, Kings College London, London, United Kingdom, ²Department of Women and Children’s Health, School of Life Course Sciences, Kings College London, London, United Kingdom, ³Centre for the Developing Brain, School of Biomedical Engineering & Imaging Sciences, Kings College London, London, United Kingdom

In this work we combine two novel methods for imaging the oxygen transfer system between maternal and fetal circulations, 1) a motion robust angiography acquisition and 2) a combined perfusion and oxygenation acquisition. This enables the matching of functional regions of placenta to the vessels that supply them in utero. This may provide further insight into the vascular origins of major obstetric diseases such as fetal growth restriction and pre-eclampsia.

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