Meeting Banner
Abstract #4090

Free breathing lung T1 mapping in idiopathic pulmonary fibrosis

Laura Saunders1, Andy Swift1, James Eaden1, and James Wild1

1Academic Radiology, University of Sheffield, Sheffield, United Kingdom

A method for free breathing Look-Locker T1 mapping using image registration is presented. This method uses a fitted model inversion recovery signal modulated with respiratory motion to create a set of synthetic images, to which all acquired free-breathing Look-Locker images are registered. The method was implemented in 9 patients with idiopathic pulmonary fibrosis (IPF) and 9 healthy volunteers and the results compared to T1 maps acquired with the same Look-Locker sequence acquired in an inspiratory breathold state for patients with IPF, and inspiratory and expiratory breath hold states for healthy volunteers. Patients with IPF were found to have a lower T1 during free breathing and a higher standard deviation of regional T1 values in the lung when compared to volunteers.

This abstract and the presentation materials are available to members only; a login is required.

Join Here