In recent years, incoherent motion in voxel has been initially applied to the diagnosis and differential diagnosis of breast lesions. Traditional single-index model DWI can not completely reflect the biological characteristics of tissue diffusion. IVIM bi-exponential model and stretched-exponential model can separate the pseudo-diffusion produced by blood flow in microvessels from the real water molecular diffusion, and accurately evaluate the benign and malignant tumor. This study intends to reflect the characteristics and changes of microstructure in breast tissues at molecular level by quantitative parameters of combined lVIM bi-exponential model and stretched-exponential model, which provides an effective basis for early detection and accurate diagnosis of breast cancer
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