The aim of this study was to compare a prototype simultaneous multi-slice single-shot echo planar imaging (SMS-ss-DWI-EPI) sequence with conventional readout-segmented echo-planar imaging (rs-DWI-EPI) for diffusion-weighted imaging of the breast at 3T magnetic resonance imaging (MRI). A reader study was conducted to evaluate image quality, lesion conspicuity and BI-RADS® score. Our results show that although the image quality with the conventional rs-DWI-EPI is superior, malignant lesions have improved visibility with the SMS-ss-DWI-EPI sequence.
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