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Abstract #4126

MRI Staging of Axillary Lymph Node Post Neoadjuvant Chemotherapy Predicts Pathological Complete Response

Renee Faith Cattell1, Julie Leong1, Thomas Ren1, James Kang1, Pauline Huang1, Ashima Muttreja1, Haifang Li1, Ankita Katukota1, Nikita Katukota1, Priya Mukhi1, Lea Baer1, Jules Cohen1, Cliff Bernstein1, Sean Clouston1, Roxanne Palermo1, and Timothy Duong1

1Stony Brook University, Stony Brook, NY, United States

This study evaluated a radiological nodal staging metric for accurate identification of diseased axillary lymph nodes (aLNs) on MRI associated with breast cancer. Comparison was made with pathological nodal staging as the ground truth. Radiological scoring of aLNs identifies diseased nodes as suspicious more correctly than it identifies normal nodes as normal. Overall, radiological scoring of the axillary lymph nodes based on morphological characteristics showed moderate accuracy in distinguishing disease or no-disease in the nodes based on standard clinical breast MRI data. Improvement in image signal-noise-ratio (SNR), spatial resolution and contrast of the axillary lymph nodes is needed.

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