Abstract #4207

Comparison of anisotropic UTE sequences for 23Na/39K imaging in the human calf at 7T

Max Müller¹, Lena V. Gast¹, Bernhard Hensel², Michael Uder¹, and Armin M. Nagel^1,3

¹Institute of Radiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany, ²Center for Medical Physics and Engineering, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany, ³Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany

Anisotropically scalable UTE sequences enable a higher in-plane resolution for X-nuclei imaging. In this work, a density-adapted 3D radial cuboid acquisition scheme is compared theoretically and experimentally against a 3D acquisition-weighted density-adapted stack-of-stars (AWSOSt) design. For the use case of ²³Na/³⁹K imaging in the human calf at 7T, it was found that, when driven at similar and clinically feasible measurement times, the AWSOSt approach provides an increased SNR at the same effective resolution. Potential T₂ blurring due to the additional phase encoding had no significant effect in this study. For both sequences a good suitability for anisotropic X-nuclei MR imaging in muscular tissue was confirmed.

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