Abstract #4223

Protocol Optimization for Functional 17O-MRI of Donor Kidneys at 3T

Yanis Taege¹, Johannes Fischer¹, Ali Çağlar Özen^1,2, Hao Song¹, Christian Schuch³, Rianne Schutter⁴, Cyril Moers⁴, Ronald JH Borra⁵, and Michael Bock¹

¹Department of Radiology, Medical Physics, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany, ²German Cancer Consortium Partner Site Freiburg, German Cancer Research Center (DKFZ), Heidelberg, Germany, ³NUKEM Isotopes GmbH, Alzenau, Germany, ⁴Department of Surgery – Organ Donation and Transplantation, University Medical Center Groningen, Groningen, Netherlands, ⁵Medical Imaging Center, University Medical Center Groningen, Groningen, Netherlands

Direct ¹⁷O-MRI is able to measure the dynamics of renal metabolism in a porcine kidney in an organ transplantation setup at 3T. To obtain stable SNRs above 20 over time while maintaining a spatial resolution below 8 mm, we investigated the influence of nominal spatial resolution, bandwidth and acquisition time window of a UTE-sequence with a golden-angle acquisition pattern on SNR. Signal increase of up to 25% per liter of ¹⁷O-gas was observed in a pilot experiment.

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