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Abstract #4228

Navigator-free Metabolite-Cycled Cardiac Proton Spectroscopy

Sophie M. Peereboom1, Mareike Gastl1, Maximilian Fuetterer1, and Sebastian Kozerke1

1Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland

Respiratory gating is a burden of conventional cardiac water-suppressed proton spectroscopy and averages are typically phase corrected based on the low-SNR triglyceride signal. Metabolite cycling allows to perform frequency and phase correction on the high-SNR water signal, which might alleviate the necessity for respiratory gating. In this work navigator-free metabolite-cycled cardiac proton spectroscopy was compared with navigator-free water-suppressed and navigator-gated water-suppressed measurements. Analyses based on relative Cramér-Rao lower bounds, creatine-to-water and triglyceride-to-water ratios were performed. Navigator-free metabolite-cycled scans were 3-4 times faster compared to conventional navigator-gated water-suppressed scans while improving signal quality.

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