Single-voxel MR spectroscopy (MRS) serves as a reference method in fat containing tissues to probe T1, T2 and proton density fat fraction (PDFF). Currently, employed techniques usually rely on long TRs to minimize T1 bias albeit the prolonged scan time and the reduced SNR efficiency. The purpose of this study is to propose the usage of a short-TR multi-inversion time (TI) multi-TE (SHORTIE) STEAM for the simultaneous assessment of T1, T2 and PDFF at reduced scan times when compared to long-TR multi-TI STEAM and long-TR multi-TE STEAM. The agreement between the aforementioned methods was tested in the exemplary application of adipose tissue characterization in the human supraclavicular fossa.
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