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Abstract #4232

Implementation of metabolite cycled liver 1H MRS on a 7T parallel transmit system

Ariane Fillmer1,2, Catalina Arteaga de Castro2, Aline Xavier2,3, Peter R. Luijten2, Dennis W. Klomp2, and Jeanine J. Prompers2

1Physikalisch-Technische Bundesanstalt (PTB), Berlin, Germany, 2Radiology, University Medical Center Utrecht, Utrecht, Netherlands, 3Biomedical Imaging Center, Pontificia Universidad Católica de Chile, Santiago, Chile

Single-voxel 1H MRS in body applications often suffers from respiratory and other motion induced phase and frequency shifts, which lead to incoherent averaging and hence to suboptimal results. Here we show the application of metabolite cycling (MC) for liver 1H MRS on a 7T parallel transmit system, using 8 transmit-receive fractionated dipole antennas with 16 additional, integrated receive loops. The preserved water signal in MC-MRS allowed for robust phase and frequency correction of individual acquisitions before coil combination and averaging, which resulted in in-vivo liver spectra with an improved spectral resolution as compared with MRS with VAPOR water suppression.

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