Abstract #4233

Functional Magnetic Resonance Spectroscopy of the Sensory and Attentional Auditory Processing at 7T

Eduardo Coello¹, Nicolas R. Bolo², George Chiou¹, Huijun Liao¹, Molly F. Charney¹, Tyler C. Starr¹, Elisabetta C. Del Re³, Margaret A. Niznikiewicz³, and Alexander P. Lin¹

¹Radiology, Brigham and Women's Hospital, Boston, MA, United States, ²Psychiatry, Beth Israel Deaconess Medical Center, Boston, MA, United States, ³Psychiatry, Veterans Affairs Boston Healthcare System, Brockton, MA, United States

This work describes a methodology to perform functional MR spectroscopy (fMRS) experiments to study auditory processing at 7T which can be valuable for gaining insight into psychiatric diseases such as schizophrenia. A reconstruction pipeline is proposed to remove distortions in the signal originated from potential temporal variations in the dynamic experiment. The designed experiment was successfully tested in healthy volunteers and metabolite variations were detected.

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