Abstract #4345

Neurovascular, muscle, and skin changes on [18F]FDG PET/MRI in foot complex regional pain syndrome (CRPS)

Daehyun Yoon¹, Yingding Xu¹, Peter Cipriano¹, Vivianne Tawfik², Catherine Curtin³, Ian Carroll², and Sandip Biswal¹

¹Radiology, Stanford University, Stanford, CA, United States, ²Anesthesiology, Stanford University, Stanford, CA, United States, ³Orthopaedics, Stanford University, Stanford, CA, United States

Complex regional pain syndrome (CRPS) is a devastating chronic pain condition affecting 50,000 new patients every year in the U.S. Unfortunately, conventional methods for examining musculoskeletal damage such as physical exam or electrodiagnostic methods are very difficult to use for CRPS patients due to their extreme sensitivity to pain. In this abstract, we demonstrate the feasibility of [18F]FDG PET/MRI for investigating musculoskeletal changes from CRPS. Our results show the improved sensitivity of [18F]FDG PET to muscular, neurovascular, and skin changes over MRI, suggesting that [18F]FDG PET/MRI can be a valuable tool to monitor the pathologic process of CRPS.

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