Abstract #4376

Fat/Water Separation and T1 and T2 Quantification Using MRF with a Rosette Trajectory in the Heart and Liver

Yuchi Liu¹, Jesse Hamilton¹, Mark Griswold^1,2, and Nicole Seiberlich^1,2

¹Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States, ²Department of Radiology, University Hospitals Cleveland Medical Center, Cleveland, OH, United States

Cardiac Magnetic Resonance Fingerprinting (cMRF) has recently been introduced for simultaneous T₁ and T₂ quantification in the myocardium. One important feature of the MRF framework is the potential to measure multiple tissue properties beyond T₁ and T₂. Here we propose an approach for simultaneous fat imaging and T₁ and T₂ quantification based on the cMRF framework with a rosette trajectory. The accuracy in T₁ and T₂ measurements and the efficacy in water-fat separation were demonstrated in the ISMRM/NIST system phantom and a multi-compartment water/oil phantom, respectively. Preliminary results in the heart and liver in healthy subjects are also shown.

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