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Abstract #4385

Toward 3D Free-breathing Cardiac Magnetic Resonance Fingerprinting

Gastao Cruz1, Olivier Jaubert1, Torben Schneider2, Aurelien Bustin1, René M. Botnar1, and Claudia Prieto1

1School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, 2Philips Healthcare, Guildford, United Kingdom

Magnetic Resonance Fingerprinting (MRF) has been introduced to simultaneously estimate multiple quantitative parameters but mainly applied to static organs. Recently the feasibility of 2D triggered cardiac MRF (cMRF) under breath-hold has been demonstrated and provides single slice simultaneous T1 and T2 maps. However, 2D cMRF provides insufficient coverage of the heart. Here we sought to develop a free-breathing 3D triggered cMRF sequence. Respiratory bellows drive an autofocus algorithm that is used to perform translation correction of respiratory motion followed by a low rank MRF reconstruction. The proposed 3D cMRF approach was evaluated in three healthy subjects, demonstrating considerable improvements in parametric maps when compared to no motion correction.

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