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Abstract #4406

Development of quantitative water content mapping in human brain at high magnetic field

Hidehiro Watanabe1, Nobuhiro Takaya1, and Fumiyuki Mitsumori1

1Center for Environmental Measurement and Analysis, National Institute for Environmental Studies, Tsukuba, Japan

The method for quantitative water content mapping of a human brain at high magnetic field was proposed. We demonstrated that B1- is proportional to B1+ in a uniform area even on a nonuniform image measured at 4.7T. B1-s of the reference phantom and a human brain can be compared by measurable B1+s in uniform areas and water content of human brain can be computed from that comparison. Our method was validated in the experiments of the mixture phantom of H2O and D2O. Quantitative water content maps of human brains were obtained by our method.

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