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Abstract #4485

Reconstruction-based Super-Resolution for High-Resolution Abdominal MRI: A Preliminary Study

Michael Ebner1,2, Premal A Patel1, David Atkinson3, Lucy Caselton3, Stuart Taylor3, Alan Bainbridge4, Sebastien Ourselin1,2, Manil Chouhan3, and Tom Vercauteren1,2

1Wellcome / EPSRC Centre for Interventional and Surgical Sciences, University College London, London, United Kingdom, 2School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, 3Centre for Medical Imaging, University College London, London, United Kingdom, 4Department of Medical Physics, University College London Hospitals NHS Trust, London, United Kingdom

Magnetic resonance (MR) cholangio-pancreatography (MRCP) is an established specialist method for imaging the upper abdomen and biliary/pancreatic ducts. Due to limitations of either MR image contrast or low through-plane resolution, patients may require further evaluation with contrast-enhanced computed tomography (CT) images. However, CT fails to offer the high tissue-ductal-vessel contrast-noise ratio available on T2-weighted MRI. MR Super-Resolution Reconstruction (SRR) frameworks can provide high-resolution visualizations from multiple low through-plane resolution single-shot T2-weighted (SST2W) images as currently used during MRCP studies. Here, we investigate the clinical potential of using additional SST2W acquisitions in multiple directions with SRR for higher diagnostic yield.

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