Meeting Banner
Abstract #4544

Sparse Pre-Contrast T1 Mapping for DCE-MRI Calibration

Zhibo Zhu1, R. Marc Lebel2, Yannick Bliesener1, and Krishna S. Nayak1

1Electrical Engineering, University of Southern California, Los Angeles, CA, United States, 2GE Healthcare, Calgary, AB, Canada

Quantitative DCE-MRI requires fast pre-contrast T1 mapping (scan time <3 min) with matching resolution and coverage. Recent advances in imaging have substantially improved resolution and coverage of DCE-MRI but without matched improvements in the pre-contrast T1 data. Here, we demonstrate a sparse T1 mapping method and characterize a tradeoff between data acquisition and T1 statistics, using a variable flip angle (VFA) approach and sparse Cartesian spiral sampling pattern, with image domain wavelet sparsity constraint. This method provides the necessary high-resolution whole-brain T1/M0 maps for DCE-MRI tracer kinetic analysis.

This abstract and the presentation materials are available to members only; a login is required.

Join Here