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Abstract #4895

Myelin UTE imaging, to be or not to be?

Kevin D Harkins1 and Mark D Does1

1Vanderbilt University, Nashville, TN, United States

This work attempts to directly image ultrashort T2 myelin signals using ultra short echo time (UTE) MRI. Long T2 water signals were suppressed using either adiabatic inversion recovery (AIR) to null signal of a single T1, or multiple adiabatic inversion recovery (MAIR) to null signal over a range of T1s. AIR-UTE showed contrast in white matter, but no such signal was observed in MAIR-UTE. These findings indicate that the AIR-UTE white matter signals are unsuppressed water signals and that the solid proton signals of myelin decay too quickly to be observed by UTE MRI.

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