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Abstract #4929

Investigation of quantitative susceptibility mapping (QSM) in diagnosis of tuberous sclerosis complex (TSC) and assessment of associated brain injuries at 1.5 Tesla

Lei Zhang1, Zhuanqin Ren1, and Xiaocheng Wei2

1Baoji Center Hospital, Baoji, China, 2GE Healthcare China, Beijing, China

Tuberous sclerosis complex (TSC) often progress to serious clinical consequences which had close relationship with cortical/subcortical tubers and white matter lesions. Quantitative susceptibility mapping (QSM) is capable of quantitatively measure the susceptibility. However, little is known about the susceptibility changes of brain damage caused by TSC. This study aims to investigated the diagnostic value of QSM in TSC. Our results suggest that QSM can shown subependymal calcified nodules and provided the quantitative information of white matter damage. So, QSM sequence may have a complementary role in the conventional MRI evaluation of tuberous sclerosis patients.

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