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Abstract #4937

Functional quantitative susceptibility mapping (fQSM) during auditory stimulation

Mauro Costagli1, Marta Lancione2, Luca Cecchetti2, Pietro Pietrini2, Mirco Cosottini3, Emiliano Ricciardi2, and Michela Tosetti1

1Imago7 and IRCCS Stella Maris, Pisa, Italy, 2IMT School for Advanced Studies, Lucca, Italy, 3University of Pisa, Pisa, Italy

Functional Quantitative Susceptibility Mapping (fQSM) has two very appealing and promising features: it is a quantitative way of mapping brain function and it is considerably less affected by the non-local effects typical of the Blood Oxygenation Level-Dependent (BOLD) signal. Here, the response of the auditory cortex to the presentation of relatively short acoustic stimuli has been studied. The majority of voxels with positive BOLD responses exhibited negative fQSM responses, while some other voxels exhibited positive fQSM repsonses, which might reflect different interplays among changes in fractional oxygen saturation, cerebral blood flow and volume.

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