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Abstract #4936

Quantitative Analysis of QSM Image for PD Basal-Cortico Circuit

Zhaoyu Lai1, Chenfei Ye1, Junyan Sun2,3, Tao Wu2,3, Junjie Liu1, Pengzheng Zhou1, Chushu Yang1, Yuan Fang1, and Ting Ma1,3

1Department of Electronics and Information, Harbin Institute of Technology, Shenzhen, China, 2Department of Neurobiology, Neurology and Geriatrics, Xuanwu Hospital Capital Medical University, Beijing Institute of Geriatrics, Beijing, China, 3National Clinical Research Center for Geriatric Disorders, Beijing, China

Parkinson’s disease is associated with iron accumulation, while quantitative susceptibility mapping can provide quantitative measures of magnetic susceptibility. To investigate the connection about iron deposition and PD etiology or progression, we focused on 16 regions in Basal-Cortico motional circuit by using quantitative susceptibility mapping. Combined with a series of Parkinson’s disease scale score, we derived the relationship between iron content and the scale scores.

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