Abstract #4962

Compensating T2 blurring in 3D TSE with Cartesian acquisition based arterial spin labeled MRI

Yiming Wang¹, Joshua S. Greer^1,2, Trevor Wigal¹, Marco C. Pinho^1,3, Joseph A. Maldjian^1,3, and Ananth J. Madhuranthakam^1,3

¹Radiology, UT Southwestern Medical Center, Dallas, TX, United States, ²Pediatrics, UT Southwestern Medical Center, Dallas, TX, United States, ³Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United States

3D fast/turbo spin echo (FSE/TSE) acquisitions are preferred for arterial spin labeled (ASL) MRI due to their higher SNR and compatibility with background suppression. However, 3D TSE suffers from T₂ blurring caused by the T₂ decay of the ASL signal along the prolonged echo train lengths, which may degrade image quality. This is often more noticeable in 3D TSE with Cartesian acquisitions. In this study, a truncated k-space filter is designed to compensate the T₂ blurring of 3D TSE with Cartesian acquisitions and improve sharpness of ASL brain perfusion images.

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