Abstract #4970

Rapid, whole-brain T1 mapping using inversion recovery EPIK (ir-EPIK): a quantitative assessment with a group of subjects

N. Jon Shah^1,2,3,4 and Seong Dae Yun¹

¹Institute of Neuroscience and Medicine 4, INM-4, Forschungszentrum Juelich, Juelich, Germany, ²Institute of Neuroscience and Medicine 11, INM-11, JARA, Forschungszentrum Juelich, Juelich, Germany, ³JARA - BRAIN - Translational Medicine, Aachen, Germany, ⁴Department of Neurology, RWTH Aachen University, Aachen, Germany

Due to their relative insensitivity to B₁ inhomogeneities, Look-Locker methods are widely used for the quantification of T₁ relaxation time. One such Look-Locker method, TAPIR, has been demonstrated with several clinical applications and has been shown to be faster than conventional gradient-echo sequences. However, it still requires a considerable acquisition time for whole-brain imaging. To overcome this limitation, a much faster method, ir-EPIK, has been presented in our earlier work. This work aims to perform a quantitative assessment of ir-EPIK in comparison to TAPIR using phantom data and twenty data sets from subjects. All data were acquired at 3T.

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