Abstract #4979

Blood oxygenation measurements in single vessels: lineshape measurements of the water signal

Lukas Buschle¹, Christian Ziener¹, Volker Sturm², Patrick Vogel³, Ke Zhang¹, Martin Bendszus², Sabine Heiland², Mirko Pham⁴, Heinz-Peter Schlemmer¹, Felix Kurz², and Thomas Kampf⁴

¹Radiology, German Cancer Research Center, Heidelberg, Germany, ²Neuroradiology, University Hospital Heidelberg, Heidelberg, Germany, ³Diagnostic and Interventional Radiology, University Hospital Wuerzburg, Wuerzburg, Germany, ⁴Neuroradiology, University Hospital Wuerzburg, Wuerzburg, Germany

In this work, the lineshape around a vessel inside a cubic voxel is analytically analyzed in dependence on the orientation of the voxel according to the external magnetic field. Results are validated with phantom measurements and in vivo measurements, that both agree very well with the developed theory. The analytical model therefore allows a determination of the oxygen extraction fraction from single voxel measurements around macroscopic vessels.

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