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Abstract #4979

Blood oxygenation measurements in single vessels: lineshape measurements of the water signal

Lukas Buschle1, Christian Ziener1, Volker Sturm2, Patrick Vogel3, Ke Zhang1, Martin Bendszus2, Sabine Heiland2, Mirko Pham4, Heinz-Peter Schlemmer1, Felix Kurz2, and Thomas Kampf4

1Radiology, German Cancer Research Center, Heidelberg, Germany, 2Neuroradiology, University Hospital Heidelberg, Heidelberg, Germany, 3Diagnostic and Interventional Radiology, University Hospital Wuerzburg, Wuerzburg, Germany, 4Neuroradiology, University Hospital Wuerzburg, Wuerzburg, Germany

In this work, the lineshape around a vessel inside a cubic voxel is analytically analyzed in dependence on the orientation of the voxel according to the external magnetic field. Results are validated with phantom measurements and in vivo measurements, that both agree very well with the developed theory. The analytical model therefore allows a determination of the oxygen extraction fraction from single voxel measurements around macroscopic vessels.

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