Abstract #4978

Oxygen Saturation Dependent Effects on Blood Transverse Relaxation at Low Fields

Dion Thomas¹, Petrik Galvosas¹, Paul D Teal², Graham A Wright³, Freya G Harrison^4,5, Max Berry^4,6, Yu-Chieh Tzeng⁴, and Sergei Obruchkov⁷

¹School of Chemical and Physical Sciences, Victoria University of Wellington, Wellington, New Zealand, ²School of Engineering and Computer Science, Victoria University of Wellington, Wellington, New Zealand, ³Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada, ⁴Centre for Translational Physiology, University of Otago, Wellington, New Zealand, ⁵Department of Surgery and Anaesthesia, University of Otago, Wellington, New Zealand, ⁶Department of Paediatrics and Child Health, University of Otago, Wellington, New Zealand, ⁷Robinson Research Institute, Victoria University of Wellington, Wellington, New Zealand

The change in T₂ due to the oxygen saturation sO₂ in blood has been well characterised at high fields, and has been successfully applied for in-vivo oximetry measurements. The effect is known to increase with B₀ field strength, but there are few studies at low field. In this work, the relationship between the T₂ relaxation rate and blood oxygenation sO₂has been characterised at a range of magnetic fields below 1 Tesla to determine whether changes in oxygenation can be practically observed and accurately quantified at lower fields.

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